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Whether you're a researcher or participant, Alethios makes health research effortless and impactful.
When building a decentralized clinical trial platform, the biggest challenge isn’t just data, design, or devices — it’s time. From structuring participant journeys, to aligning “Day One” across a cohort, to timing instruments and reminders, Alethios has engineered time into the platform itself.
When you set out to build a decentralized clinical trial platform, you might expect the focus to be on data, design, or devices. But spend any amount of time in the trenches, and you realize: what you’re really building is a system around time.
In traditional site-based trials, time is controlled by the clinic. Visits are scheduled, instruments are administered in person, and participants are observed in the same physical environment. In decentralized trials, none of that is guaranteed. Participants are at home, on their own schedules, and in their own contexts.
To create a structured and controlled environment remotely, we’ve had to engineer time into the platform itself. In honor of our engineering team’s work with this invisible but essential dimension, here are a few places where time has proven crucial for high-quality, repeatable, and reputable studies.
Every study begins with a funnel: screening → consent → randomization → onboarding/baseline → study schedule.
In a clinic, this flow is handled by staff. In decentralized research, it has to be engineered. Each stage must be staggered, trackable, and transparent so that participants know where they are in the process, just as a researcher would. Giving participants a sense of place on their timeline improves both adherence and confidence — they know exactly what comes next, and when.
In decentralized trials, each participant’s Day One is self-determined. Someone may start the study the day they receive their kit, while another might begin a week later. That variability is natural — but it poses challenges for comparing data across participants.
We’ve solved this through our Distribute feature. Researchers can configure which items in a study kit are required before a participant begins their study schedule. This ensures that “Day One” is aligned across the cohort for analysis, even if logistics differ for each individual. Getting everyone onto a common clock is critical for making comparisons valid and results interpretable.
Not all instruments are created equal — and not all can be answered at any time of day.
Take a lunchtime survey in a GLP-1 study, for example. To be valid, it must be available in a fixed window (say 12–2 p.m.) and send reminders during that window. The context matters: you want participants answering while they’re in the same frame of mind or situation, not recalling it hours later.
That’s why we’ve built instrument scheduling around local time zones and time-limited availability. By catching participants when the measure is most relevant, we improve both the quality of the data and the consistency of the responses.
Time may be invisible, but it’s everywhere in decentralized research. From participant journeys, to synchronized Day Ones, to carefully timed instruments, our engineering team has built Alethios around it.
The result is not just a platform that makes decentralized studies possible, but one that makes them structured, comparable, and credible.
In clinical research, time has always mattered. In decentralized research, it matters even more.
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Whether you're a researcher or participant, Alethios makes health research effortless and impactful.
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