Post-GLP-1 Weight Maintenance Study

Help us learn how a natural green coffee extract may support weight maintenance after weight loss using a GLP-1 (e.g. Zepbound, Ozempic).
See if you qualify

This is a 12-week research study looking at a natural, decaffeinated green coffee extract and its role in helping people maintain their weight after losing it while on a GLP-1 agonist medication. Keeping weight off is a real challenge for many people, and this study aims to better understand what may help. If you join, you'll take a daily supplement and complete simple health tracking from home.

About This Study

Fully Remote Study
Take part from the comfort of your home. All check-ins, surveys, and study tasks happen through your iPhone — no clinic visits needed.
Simple At-Home Testing
You'll collect a few small drops of blood at home using an easy dried blood spot kit that we mail to you at the beginning and end of the study. You'll also wear a continuous glucose monitor for the first and last two weeks of the three month study to see changes in your blood sugar.
Compensation Provided
You'll be compensated for your time and effort throughout the study with a $150 Amazon Gift Card, your study data returned to you and a free smart scale that you can keep once the study is completed.
Track Your Progress
Use a smart scale and a continuous glucose monitor to see how your body responds during the 12-week study. All tasks will be completed on your Alethios dashboard.

What's Involved

You'll take one capsule twice a day before a meal for 12 weeks. Along the way, you'll wear a continuous glucose monitor, use a smart scale, log your meals with photos, collect a few at-home blood spot samples, and complete short surveys about your eating habits, mood, and quality of life. Everything is done from home using your smartphone or desktop computer.

Check If You Qualify

Answer a few quick questions online to see if this study may be a good fit for you. It only takes a few minutes.

Get Started at Home

If you qualify, you'll set up the study app, receive your kit, and complete your first measurements and surveys to record your starting point.

Follow the Daily Routine

Take one capsule twice a day before a meal, wear your glucose monitor, log your food, and complete short surveys and check-ins over 12 weeks.

Wrap Up and Get Paid

Complete your final measurements and surveys at week 12, then receive your compensation for taking part.

What's Being Studied?

The study measures changes in body weight, body composition, blood sugar, and cholesterol, along with eating habits and overall well-being. Researchers want to see whether the green coffee extract helps people maintain their weight compared to a placebo. Understanding this could help support healthier weight maintenance in the future.

Am I eligible?

You may be eligible if you meet the following requirements

See if you qualify
Adults aged 20 to 60 years
Body mass index (BMI) between 18.5 and 30
In good general health
Recently finished a weight loss program using medication (such as a GLP-1) or another approved method within the last month
Lost more than 5% of your body weight within the past 12 months and have kept most of it off
Own an iPhone (iOS device)
Not diagnosed with diabetes and not taking glucose-lowering medication
Not pregnant or breastfeeding
Do not use tobacco, nicotine, or cannabis products
Not currently taking supplements for metabolic support or rich in chlorogenic acids